KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1E
All Species:
13.03
Human Site:
S2213
Identified Species:
28.67
UniProt:
Q15878
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15878
NP_000712.2
2313
261731
S2213
C
L
T
E
S
S
N
S
P
H
P
Q
Q
S
Q
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
Q2662
P
I
H
F
A
G
A
Q
T
S
L
P
A
F
S
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S2210
C
L
T
E
S
S
N
S
P
H
P
R
Q
G
Q
Dog
Lupus familis
XP_547425
2465
277756
Q2365
G
H
G
Q
G
H
G
Q
G
H
G
Q
Q
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61290
2272
257217
S2173
C
L
T
E
S
S
N
S
L
H
P
Q
Q
G
Q
Rat
Rattus norvegicus
Q07652
2222
252098
S2122
C
L
T
E
S
S
N
S
L
H
P
Q
Q
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
L2095
D
S
L
V
E
A
V
L
I
S
E
G
L
G
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
T1737
N
D
N
E
P
P
E
T
E
G
L
I
A
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
L1759
R
E
R
D
R
E
R
L
R
D
R
D
R
D
R
Honey Bee
Apis mellifera
NP_001159376
1904
215872
L1812
N
K
P
S
T
L
Q
L
K
P
A
N
I
N
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
K1874
R
N
S
G
G
G
S
K
G
D
V
R
L
Q
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
95.8
90.7
N.A.
94.6
92.5
N.A.
N.A.
26.4
N.A.
20.4
N.A.
43.5
46.2
N.A.
39.5
Protein Similarity:
100
57.8
96.3
92
N.A.
95.8
93.8
N.A.
N.A.
41.9
N.A.
37.4
N.A.
55.8
57.8
N.A.
52.5
P-Site Identity:
100
0
86.6
33.3
N.A.
86.6
86.6
N.A.
N.A.
0
N.A.
6.6
N.A.
0
0
N.A.
0
P-Site Similarity:
100
13.3
93.3
40
N.A.
86.6
86.6
N.A.
N.A.
13.3
N.A.
20
N.A.
20
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
10
0
0
0
10
0
19
0
0
% A
% Cys:
37
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
10
0
0
0
0
0
19
0
10
0
10
0
% D
% Glu:
0
10
0
46
10
10
10
0
10
0
10
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
10
% F
% Gly:
10
0
10
10
19
19
10
0
19
10
10
10
0
37
0
% G
% His:
0
10
10
0
0
10
0
0
0
46
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
10
0
0
10
10
0
0
% I
% Lys:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
10
% K
% Leu:
0
37
10
0
0
10
0
28
19
0
19
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
19
10
10
0
0
0
37
0
0
0
0
10
0
10
0
% N
% Pro:
10
0
10
0
10
10
0
0
19
10
37
10
0
0
0
% P
% Gln:
0
0
0
10
0
0
10
19
0
0
0
37
46
10
46
% Q
% Arg:
19
0
10
0
10
0
10
0
10
0
10
19
10
10
19
% R
% Ser:
0
10
10
10
37
37
10
37
0
19
0
0
0
19
10
% S
% Thr:
0
0
37
0
10
0
0
10
10
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
10
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _